A new (standard) definition of Molecular Imaging is formulated by Molecular Imaging Center of Excellence (MICoE) standard definitions Task Force and SNM.
"Molecular imaging is the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems. To elaborate; Molecular imaging typically includes 2- or 3-dimensional imaging as well as quantification over time. The techniques used include radiotracer imaging/nuclear medicine, MR imaging, MR spectroscopy,optical imaging, ultrasound,and others."
The group also defined related terminologies:
"Molecular imaging agents are probes used to visualize, characterize, and measure biological processes in living systems. Both endogenous molecules and exogenous probes can be molecular imaging agents."
"Molecular imaging instrumentation comprises tools that enable visualization and quantification in space and over time of signals from molecular imaging agents."
"Molecular imaging quantification is the determination of regional concentrations of molecular imaging agents and biological parameters. Further, molecular imaging quantification provides measurements of processes at molecular and cellular levels. This quantification is a key element of molecular imaging data and image analysis,especially for inter- and intrasubject comparisons."
Other key statements regarding MI were
"Molecular imaging is the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems. To elaborate; Molecular imaging typically includes 2- or 3-dimensional imaging as well as quantification over time. The techniques used include radiotracer imaging/nuclear medicine, MR imaging, MR spectroscopy,optical imaging, ultrasound,and others."
The group also defined related terminologies:
"Molecular imaging agents are probes used to visualize, characterize, and measure biological processes in living systems. Both endogenous molecules and exogenous probes can be molecular imaging agents."
"Molecular imaging instrumentation comprises tools that enable visualization and quantification in space and over time of signals from molecular imaging agents."
"Molecular imaging quantification is the determination of regional concentrations of molecular imaging agents and biological parameters. Further, molecular imaging quantification provides measurements of processes at molecular and cellular levels. This quantification is a key element of molecular imaging data and image analysis,especially for inter- and intrasubject comparisons."
Other key statements regarding MI were
- it personalizes patient care such as in several cardiovascular, cancer and neurological disorders.
- it is useful in drug discovery and development --to characterize pharmacokinetics and pharmacodynamics.
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