Saturday, June 09, 2007

Molecular imaging expands its boundaries

The highlights of the recently concluded SNM meeting in which molecular imaging research had been given a profound boost are well summarized in the following link.
Molecular imaging expands its boundaries - MedicalPhysicsWeb
Key take-home points are
  • FDG-PET can accurately identify a patient's response to neoadjuvant therapy for esophageal cancer. (MUNICON trial of 110 patients)
  • FLT-PET can determine brain tumor (recurrent malignant gliomas) patients' response to drugs within one or two weeks of treatment initiation. (UCLA trial of 19 patients)
  • Combined myocardial perfusion SPECT+64-slice CT angiography can increase the accuracy of coronary artery disease diagnosis.
  • PET-CT using a novel CT contrast agent (N1177 - a macrophage specific nanoparticulate contrast agent) can detect high risk atherosclerotic plaques.
  • PET-CT imaging can effectively diagnose graft infection and differentiate it from surrounding soft-tissue infection. (A study in Israel on 39 patients with 69 vascular grafts)
  • PET-CT is invaluable in the management of patients with suspected recurrent ovarian carcinoma. (A multicenter study in Australia on 90 patients)
  • PET-CT is invaluable for non-invasively monitoring Crohn's disease. (A study in Belgium on 22 patients)

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